Monday, December 22, 2008

The DNA Assembler - Rapidly Construct Biochemical Pathways

Researchers at the University of Illinois at Urbana-Champaign have created the DNA Assembler, a novel way to rapidly construct biochemical pathways in yeast. The DNA Assembler incorporates homologous recombination to allow scientists to assemble entire biochemical pathways in a single step only requiring a simple DNA prep and a one-step yeast transformation. Advantages of the DNA assembler method include:

- Assembly of multiple-gene biochemical pathways in a single step.

- Most rapid and efficient approach to construct large recombinant DNA molecules.

It can be used to construct custom-designed DNA molecules not only on a plasmid but also on a chromosome with the potential to assemble a very large biochemical pathway or even a whole genome.The DNA Assembler represents a powerful tool in the construction of biochemical pathways for synthetic biology, metabolic engineering and functional genomics studies. To learn more about it read the original paper published in the Dec 12th issue of Nucleic Acids Research,http://nar.oxfordjournals.org/cgi/content/short/gkn991v1?rss=1

HumanZyme's cytokines

Aren't all cytokines the same? Not HumanZyme's. HumanZyme has developed an innovative technology for the efficient production of large amounts of cytokines in human cells, unlike most cytokines on the market today which are grown in bacteria. Why are HumanZyme's cytokines better than the enzymes you are using right now? Because of the proprietary technology used to produce HumanZyme's cytokines, they have:

Human-specific glycosylation patterns
Longer-half-life in culture
Other human post-translational modifications

What does that mean to you? When performing research using human cells, cytokines with human specific glycosylation patterns show increased biological activity and substantially higher stability. When working with cultured cells, this results in fewer media changes thus decreasing your reagent cost, your time spent on maintenance, and your chance of contamination. To learn more about HumanZyme's cytokines, visit their site at http://www.humanyme.com/.

Do you have an exciting new product you would like reviewed? If so, email me at mailto://products@redbridgemarketing.com with detailed information about your product.

Shotgun protein sequencing

What is shotgun protein sequencing? It is a new, quicker way to sequence monoclonal antibodies that was developed by bioinformatics researchers at the University of California, San Diego and Genentech. It is a new protein sequencing method that reduces the time required to sequence an unknown antibody to under 36 hours. Currently, it takes weeks to months to sequence an antibody.

This technique is described in detail in the article “Automated de novo protein sequencing of monoclonal antibodies” published in the December 2008 issue of Nature Biotechnology.

Wednesday, December 17, 2008

Bath Armor - eliminate water bath contamination

Lab Armor's newest product, Bath Armor, is a dry, sterilizable, highly conductive thermal media that replaces water in water baths. Water baths are perfect for incubating experiments, but they also incubate microbes increasing the risk of contamination of your experiments.

Bath Armor also cuts down on lab maintenance and equipment costs. You don't have to clean and refill your water baths as often, and it doesn't evaporate, so water baths can be left on continually without causing water bath burnout. To read more about Bath Armor see http://www.labarmor.com/shop_bath_armor.html.

Do you have an exciting new product you would like reviewed? If so, email the detailed information about your product to products@redbridgemarketing.com.