The DNA Assembler - Rapidly Construct Biochemical Pathways

Researchers at the University of Illinois at Urbana-Champaign have created the DNA Assembler, a novel way to rapidly construct biochemical pathways in yeast. The DNA Assembler incorporates homologous recombination to allow scientists to assemble entire biochemical pathways in a single step only requiring a simple DNA prep and a one-step yeast transformation. Advantages of the DNA assembler method include:

- Assembly of multiple-gene biochemical pathways in a single step.

- Most rapid and efficient approach to construct large recombinant DNA molecules.

It can be used to construct custom-designed DNA molecules not only on a plasmid but also on a chromosome with the potential to assemble a very large biochemical pathway or even a whole genome.The DNA Assembler represents a powerful tool in the construction of biochemical pathways for synthetic biology, metabolic engineering and functional genomics studies. To learn more about it read the original paper published in the Dec 12th issue of Nucleic Acids Research,http://nar.oxfordjournals.org/cgi/content/short/gkn991v1?rss=1