Tuesday, July 14, 2009

Sensitive Detection of Melamine Contamination

Today BIOO Scientific announced the expansion of its portfolio of food safety testing solutions with a new kit which improves the detection of melamine in food. Melamine contamination has recently been identified in infant formula and other milk-based products from China. Melamine is a dangerous, nitrogen rich organic compound that is illegally added to food and feed to increase the apparent protein content values of food products. Consumption of melamine causes highly insoluble melamine cyanurate crystals to form in the kidney, which damage renal cells and can result in renal failure or death. The recent establishment of a 1µg/g (1ppm) safety threshold for melamine in infant foods has led to an immediate need for sensitive melamine detection methods.

Bioo Scientific’s MaxSignal Melamine Enzymatic Assay Kit has been developed to meet the industry’s need for increased sensitivity. The MaxSignal Melamine Enzymatic Assay Kit is a rapid, inexpensive aqueous extraction method that is able to detect down to 0.2 ppm of melamine. According to Dr Joe Krebs, Director of Protein Chemistry and Engineering at Bioo Scientific, “The MaxSignal Melamine Enzymatic Assay Kit does not require expensive and time-consuming mass spectrometry and immunoassay techniques characteristic of currently available methods. Our novel enzyme-based method offers food safety analysts a new choice for sensitive and cost-effective melamine detection in food samples.”

Tuesday, June 2, 2009

Bioo Scientific’s Toxicity Assay Kits Increase the Efficiency of Drug Development

Since toxicity is one of the leading causes of drug failures, measuring preclinical toxicity is a critical drug development function. Accurate in vivo toxicity assays are essential to lowering attrition and increasing efficiency in drug development.

Bioo Scientific announced today the launch of their MaxDiscovery™ Toxicity Assay Kits. These kits monitor in vivo toxicity by measuring liver and heart function in serum samples. They provide simple, convenient, colorimetric determination of well-characterized functional markers of for liver and heart. They are ideal tools to monitor toxic effects caused by administration of siRNA, DNA plasmids, transfection agents or other therapeutic treatments during preclinical studies. The assays can be used in a range of mammals, including mice and rats, providing a powerful tool to assess and reduce the toxicity of drugs formulations and to improve drug delivery methods.

According to Dr Joe Krebs, Director of Protein Chemistry and Engineering at Bioo Scientific, “MaxDiscovery™ Toxicity kits are designed to provide researchers with rapid, cost-effective tools required to address the escalating challenges of drug development in today's competitive landscape.”

Assays are available for alanine transaminase, aspartate transminase, alkaline phosphatase, lactate dehydrogenase, cholesterol, and creatine kinase.

About Bioo Scientific
Bioo Scientific Corporation is a global biotechnology tools company, headquartered in Austin, Texas. Bioo Scientific provides innovative products and services to academic researchers, pharmaceutical and biotechnology companies, molecular diagnostics laboratories, and customers who perform food and feed safety analysis.

Monday, April 27, 2009

Efficient In Vivo siRNA Delivery

MaxSuppressor™ In Vivo RNA-LANCEr™ II is an exciting new product from Bioo Scientific that simplifies in vivo RNAi experiments. The RNA-LANCEr II is a non-viral transfection agent optimized for the efficient in vivo introduction of siRNA, miRNA, and other RNAi agents directly into tissues. It is easy to use – simply mix with your RNAi agent, extrude or sonicate the mixture, and inject it into your animal. MaxSuppressor In Vivo RNA-LANCEr II offers consistent, reliable silencing using minimal amounts of RNAi agents. To learn more about how Bioo Scientific's MaxSuppressor In Vivo RNA-LANCEr II can simplify you in vivo RNAi experiments visit Bioo Scientific.

Monday, December 22, 2008

The DNA Assembler - Rapidly Construct Biochemical Pathways

Researchers at the University of Illinois at Urbana-Champaign have created the DNA Assembler, a novel way to rapidly construct biochemical pathways in yeast. The DNA Assembler incorporates homologous recombination to allow scientists to assemble entire biochemical pathways in a single step only requiring a simple DNA prep and a one-step yeast transformation. Advantages of the DNA assembler method include:

- Assembly of multiple-gene biochemical pathways in a single step.

- Most rapid and efficient approach to construct large recombinant DNA molecules.

It can be used to construct custom-designed DNA molecules not only on a plasmid but also on a chromosome with the potential to assemble a very large biochemical pathway or even a whole genome.The DNA Assembler represents a powerful tool in the construction of biochemical pathways for synthetic biology, metabolic engineering and functional genomics studies. To learn more about it read the original paper published in the Dec 12th issue of Nucleic Acids Research,http://nar.oxfordjournals.org/cgi/content/short/gkn991v1?rss=1

HumanZyme's cytokines

Aren't all cytokines the same? Not HumanZyme's. HumanZyme has developed an innovative technology for the efficient production of large amounts of cytokines in human cells, unlike most cytokines on the market today which are grown in bacteria. Why are HumanZyme's cytokines better than the enzymes you are using right now? Because of the proprietary technology used to produce HumanZyme's cytokines, they have:

Human-specific glycosylation patterns
Longer-half-life in culture
Other human post-translational modifications

What does that mean to you? When performing research using human cells, cytokines with human specific glycosylation patterns show increased biological activity and substantially higher stability. When working with cultured cells, this results in fewer media changes thus decreasing your reagent cost, your time spent on maintenance, and your chance of contamination. To learn more about HumanZyme's cytokines, visit their site at http://www.humanyme.com/.

Do you have an exciting new product you would like reviewed? If so, email me at mailto://products@redbridgemarketing.com with detailed information about your product.

Shotgun protein sequencing

What is shotgun protein sequencing? It is a new, quicker way to sequence monoclonal antibodies that was developed by bioinformatics researchers at the University of California, San Diego and Genentech. It is a new protein sequencing method that reduces the time required to sequence an unknown antibody to under 36 hours. Currently, it takes weeks to months to sequence an antibody.

This technique is described in detail in the article “Automated de novo protein sequencing of monoclonal antibodies” published in the December 2008 issue of Nature Biotechnology.

Wednesday, December 17, 2008

Bath Armor - eliminate water bath contamination

Lab Armor's newest product, Bath Armor, is a dry, sterilizable, highly conductive thermal media that replaces water in water baths. Water baths are perfect for incubating experiments, but they also incubate microbes increasing the risk of contamination of your experiments.

Bath Armor also cuts down on lab maintenance and equipment costs. You don't have to clean and refill your water baths as often, and it doesn't evaporate, so water baths can be left on continually without causing water bath burnout. To read more about Bath Armor see http://www.labarmor.com/shop_bath_armor.html.

Do you have an exciting new product you would like reviewed? If so, email the detailed information about your product to products@redbridgemarketing.com.